What Is Diabetes?

Diabetes is a group of health conditions that are defined by high blood sugar (glucose) levels. There are several forms of diabetes, all of which involve some dysfunction in the use or production of the hormone insulin, which allows the body to use sugar in the bloodstream for energy.
Though different types of diabetes have different causes, they tend to have similar symptoms and complications. There is no cure for diabetes, and some forms of the disease are lifelong, but all can be treated and managed with diet, exercise, and medication.
Types of Diabetes
Diabetes 101: What Are the Different Types of Diabetes?

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Type 2 Diabetes
Type 2 diabetes results from insulin resistance, an inability to use the hormone insulin properly. As the body’s demand for insulin increases, the pancreas may struggle to produce enough of the hormone to maintain healthy blood glucose levels.
The condition typically develops in people older than 45, but the incidence of type 2 diabetes in children is also on the rise.
Prediabetes
Prediabetes is not technically a form of diabetes, but it can lead to type 2 diabetes.
Type 1 Diabetes
Type 1 diabetes is an autoimmune disorder in which a person’s own immune system attacks and destroys the cells in the pancreas that make insulin. As natural insulin production declines, blood glucose levels can rise to life-threatening levels. The symptoms of type 1 diabetes can come on very quickly, especially in the young. Sometimes the condition isn’t identified until a patient has experienced a deadly condition named diabetic ketoacidosis (DKA).
People with type 1 diabetes must take insulin every day to replace the insulin their bodies don’t make, as well as monitor their blood glucose levels daily.
Despite these advancements, people with type 1 diabetes still face daily risks of hypoglycemia (low blood sugar), and blood sugar management can be a demanding balancing act.
Latent Autoimmune Diabetes in Adults (LADA, or Type 1.5 Diabetes)
People with LADA may not need insulin for years. Instead, lifestyle changes and medications for type 2 diabetes, such as metformin or GLP-1s, may temporarily keep blood glucose levels in a healthy range.
As their natural insulin production declines, people with LADA tend to find that these early treatment methods are no longer effective. Ultimately, they need daily insulin therapy.
People with LADA eventually need to follow guidelines pertaining to type 1 diabetes for ongoing management.
Maturity-Onset Diabetes of the Young (MODY)
While its symptoms are similar to those of other types of diabetes, MODY is fundamentally different from type 1 and type 2 diabetes.
MODY:
- Typically develops during adolescence or early adulthood before age 25
- Isn’t caused by the immune system or insulin resistance
- Is frequently misdiagnosed as type 1 or type 2 diabetes
- Is typically treated with non-insulin diabetes medications
Neonatal Diabetes
Neonatal diabetes can be transient, which means it can resolve by itself, though it may possibly return later in life. It can also be permanent, requiring daily insulin therapy indefinitely.
Signs and symptoms of neonatal diabetes include:
- Inadequate weight gain
- Dehydration
- High blood sugar
This form of diabetes can often be managed with type 2 diabetes medications, such as sulfonylureas, rather than insulin.
Gestational Diabetes
Pregnant women develop gestational diabetes during about 14 percent of all pregnancies in the United States. To help ensure there’s enough glucose available to provide energy for a growing fetus, pregnant women normally develop a certain amount of insulin resistance, and sometimes this causes blood sugar to increase to the diabetic range.
Typically, treatment for gestational diabetes focuses on diet and lifestyle changes, but sometimes doctors prescribe oral diabetes medications or insulin to keep blood sugar in a healthy range.
Gestational diabetes can lead to complications that affect the health of both the mother and child. Women with gestational diabetes have a higher risk of preeclampsia, and their infants are more likely to be born prematurely or have a higher than normal birth weight, creating complications during delivery. The infants can also go on to develop dangerously low blood sugar levels soon after birth. Later in life, they have an increased risk of developing obesity, heart disease, and type 2 diabetes.
Type 3 Diabetes
Type 3c Diabetes
Type 3c diabetes, also known as pancreatogenic or pancreatic diabetes, is caused by direct damage to the pancreas. This damage can be caused by conditions such as chronic pancreatitis or cystic fibrosis, or by surgical removal of the pancreas (pancreatectomy).
Steroid-Induced Diabetes
Signs and Symptoms of Diabetes
- Increased thirst
- Increased hunger
- Frequent urination
- Unexplained weight loss
- Fatigue
- Blurred vision
- Numbness or tingling in the hands or feet
- Sores or cuts that heal slowly or not at all
- Frequent infections
If you’re experiencing any combination of these symptoms, visit your doctor or urgent care center immediately for evaluation. Undiagnosed diabetes can be extremely dangerous.

Causes and Risk Factors of Diabetes
Some forms of diabetes, including type 1 diabetes, LADA, MODY, neonatal diabetes, and type 3c diabetes, cannot be prevented. But you can take steps to lower your chance of developing types of diabetes that result from insulin resistance, such as prediabetes, type 2 diabetes, and gestational diabetes.
Diabetes Risk Factors: Where You Can Take Action
- Excess weight
- A diet that’s high in fat, added sugar, and refined carbohydrates
- Lack of regular exercise
- Tobacco use
- High blood pressure, low HDL (“good”) cholesterol, and high triglycerides
- Poor sleep quality, which can contribute to an increase in stress hormones like cortisol, worsening insulin resistance
- Stress and other treatable mental health conditions
Diabetes Risk Factors You Can’t Control
- Age
- A family history of diabetes
- Alaska Native, American Indian, Asian American, Black, Hispanic or Latino, Native Hawaiian, or Pacific Islander ethnicity
- A history of gestational diabetes or a child with a birth weight of 9 pounds or more
- Polycystic ovary syndrome (PCOS)
How Is Diabetes Diagnosed?
Diabetes is diagnosed using one or more blood sugar tests.
Fasting Plasma Glucose Test
- Less than 100 milligrams per deciliter (mg/dL) is considered normal
- 100 to 125 mg/dL indicates prediabetes
- 126 mg/dL or higher indicates diabetes
Random Plasma Glucose Test
Hemoglobin A1C Test
- Below 5.7 percent is considered normal
- Between 5.7 and 6.4 percent indicates prediabetes
- 6.5 percent and higher indicates diabetes
Additional Testing
While blood sugar tests can reveal whether a person has diabetes, they cannot always identify the type of diabetes. A healthcare provider may choose to administer additional tests in order to determine if an individual has type 1 diabetes, type 2 diabetes, or a rarer form of the disease.
- Autoantibody Tests These tests, which look for antibodies targeting insulin or certain pancreatic cells, are conducted most often to diagnose type 1 diabetes or LADA.
- C-Peptide Test This test measures the amount of a protein that mirrors the level of insulin in the body, low levels of which can indicate type 1 diabetes or LADA.
- Genetic Testing MODY and neonatal diabetes may be detected using genetic testing.
Sometimes these additional tests are administered long after an initial diabetes diagnosis, especially if treatment has proven ineffective.
Treatment and Medication Options for Diabetes
If you’ve been diagnosed with diabetes, your treatment regimen will depend on your individual health and the type of diabetes you’re managing.
Blood Sugar Testing
Diabetes treatment is defined by blood sugar management, and it’s essential to measure and track your blood sugar levels if you want to understand your condition. You may be advised to check your blood sugar only occasionally, or multiple times every day, including before every meal.
A traditional glucose meter requires you to prick your finger with a lancing device, then place the blood drop on a disposable test strip that’s inserted into the meter. The meter will show you your current blood sugar level.
Insulin
Not everyone with diabetes requires insulin, but some people will require regular injections of the hormone in order to keep their blood sugar levels in a safe range.
Many people with type 1 diabetes will need insulin immediately and can expect to need it every day for the rest of their lives. People with LADA don’t need insulin when they are diagnosed, but will eventually develop an absolute need for insulin. Some people with other forms of diabetes, including type 2 diabetes, will also be prescribed insulin, though they may not need it as soon as they’re diagnosed.
Different types of insulin are categorized by how quickly they reduce blood sugar levels:
- Basal insulin, or long-acting insulin, covers the body’s background insulin needs, working steadily over 24 hours. This may be the first type of insulin that you are prescribed.
- Bolus insulin, also known as rapid-acting or mealtime insulin, lowers blood sugar levels quickly, and is most often before or during meals.
All types of insulin carry a danger of low blood sugar (hypoglycemia) and require training to be used safely.
Other Glucose-Lowering Medications
When treating type 2 diabetes, non-insulin medications are the first line of defense.
- DPP-4 inhibitors increase your pancreas’s natural insulin production after meals and tell your liver to produce less sugar by inhibiting the enzyme that breaks down your body’s endogenous GLP and GIP hormones.
- GLP-1 receptor agonists mimic the hormone GLP-1 to lower blood sugar levels. They work in several ways, including decreasing appetite, increasing insulin sensitivity, delaying digestion, and decreasing liver glucose production. Weight loss is a known benefit, which further helps improve insulin sensitivity and blood glucose levels.
- GLP-1/GIP receptor agonists work similarly to GLP-1 receptor agonist medications. They reduce blood glucose levels, improve insulin sensitivity, support weight loss, and regulate cholesterol levels.
- Meglitinides tell the pancreas to produce more insulin when you’re eating.
- Metformin works by telling the liver to produce less glucose and boosting insulin sensitivity.
- SGLT2 inhibitors work by passing excess sugar from your bloodstream through your urine, requiring your kidneys to remove the extra sugar.
- Sulfonylureas tell the pancreas to release more insulin with meals.
- Thiazolidinediones improve your body's overall sensitivity to insulin.
Surgery
Prevention of Diabetes
Key risk factors you can manage include:
- Excess weight
- A diet high in fats, sugars, and refined carbohydrates
- Lack of exercise
- Tobacco use
- High blood pressure, low HDL cholesterol, high triglycerides, and heart disease
- Poor sleep habits
- Chronic stress
Lifestyle Changes for Diabetes
Focus on Wholesome Food
- Eat lots of nonstarchy vegetables.
- Avoid added sugar and refined starches like flour or white rice.
- Choose whole foods and ingredients rather than highly processed foods.
People with diabetes can work with dietitians for support in adopting a diet that fits their personal nutrition needs and cultural preferences. Popular diets today include the ketogenic, low-carbohydrate, Mediterranean, vegetarian, vegan, and DASH diets, all of which can be diabetes-friendly. The ideal diet for you may take into account several features of each diet without intense adherence to one protocol entirely.
Get Regular Exercise
Other Lifestyle Factors
Changes in your daily lifestyle habits can significantly decrease your risk of developing prediabetes, gestational diabetes, and type 2 diabetes. Such lifestyle factors include:
- Maintain a healthy weight. Preventing weight gain, losing weight, and maintaining a healthy weight is critical to prevent diabetes or achieve remission. Excess body fat significantly decreases insulin sensitivity.
- Quit all forms of tobacco use. Nicotine both elevates blood glucose levels and causes insulin resistance. Quitting smoking can improve your circulation, reduce overall inflammation, and improve insulin sensitivity.
- Manage your alcohol consumption. Excessive alcohol consumption can increase your risk of diabetes by reducing liver and pancreas function and thereby affecting your body’s blood glucose control. Reduce and manage your alcohol consumption to lower your risk of diabetes.
- Get better sleep. A number of sleep problems, including insomnia and obstructive sleep apnea, are associated with insulin resistance, prediabetes, and diabetes.
- Address your stress. Chronic stress can increase your risk of diabetes primarily through the overproduction of stress-related hormones like cortisol. Incorporate relaxation techniques such as meditation, deep breathing, and regular exercise to keep cortisol levels in check.
What Is Diabetes Burnout?
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Prognosis and Outlook of Diabetes
While some forms of diabetes are lifelong conditions, you can live a full life with any type of diabetes. The specific prognosis for life with diabetes varies depending on the type, your daily management of the condition, and your overall health.
Other forms of diabetes, like MODY, LADA, or diabetes from other causes, require specific care and support. As with other types of diabetes, working to manage healthy blood glucose levels is critical to improving long-term health.
Complications of Diabetes
Major long-term complications of diabetes include:
- Cardiovascular disease, such as heart attack and stroke
- Neuropathy, which can lead to foot or lower limb amputation in severe cases
- Kidney disease, which can require dialysis or a kidney transplant in advanced cases
- Retinopathy, which can lead to vision loss
Other potential long-term complications of diabetes include:
- Bladder problems and sexual dysfunction
- Gastroparesis (dysfunction of the stomach muscles)
- Skin problems
- Hearing loss
- Hair loss
- Depression and mental health issues
Diabetes can also create a number of short-term dangers:
- Hypoglycemia (low blood glucose) is a risk for anyone taking insulin or non-insulin medications like sulfonylureas. Left untreated, hypoglycemia can lead to lightheadness, confusion, diabetic seizure, and even death.
- Diabetic ketoacidosis (DKA) occurs when the body doesn’t have enough insulin to convert glucose into energy. It begins to break down fat for fuel, producing ketones at toxic levels. Left untreated, it can lead to seizures, coma, and death. DKA is most common in people with type 1 diabetes.
- Hyperglycemic hyperosmolar nonketotic syndrome is an emergency caused by chronically high blood glucose levels. It’s most common in people with type 2 diabetes.
Research and Statistics
Diabetes affects people across the globe of all ages, ethnicities, and genders. Diabetes rates are rising in almost every country, and the disease has been widely described as a pandemic.
Disparities and Inequalities in Diabetes
Diabetes disproportionately affects certain racial and ethnic groups in the United States. Experts believe that the differences are largely due to social determinants of health, including access to affordable healthcare, insurance coverage, education, and healthy food.
- Less likely to be prescribed a continuous glucose monitor (CGM) or insulin pump
- Less likely to be educated on new diabetes technology or medications
- More likely to develop diabetes-related complications like neuropathy and retinopathy
- More likely to experience frequent episodes of severe hypoglycemia that require hospitalization
- More likely to experience DKA and require hospitalization
Support for People With Diabetes
African American Diabetes Association
This organization aims to address the unique challenges faced by African Americans with any type of diabetes, including prevention, management, and education. It provides culturally conscious resources and support groups to help improve diabetes health and raise awareness about inequities in healthcare.
Diabetes Sisters
This nonprofit supports women with any type of diabetes, offering in-person and virtual meets, free educational resources, and educational webinars. The organization aims to empower women of all ages and diabetes types by discussing common challenges and providing real-life management support.
This nonprofit focuses primarily on supporting children, teens, and young adults with type 1 diabetes through in-person Wiffle tournaments, fundraising, sponsorships for Division I college athletes, and events across the country. By pairing sports and diabetes awareness, SLAMT1D empowers young people to challenge the stereotypes and stigma of type 1 diabetes, encouraging them to live active, fulfilling lives.
This organization strives to help young adults with type 1 and type 2 diabetes transition to adulthood by providing resources on health management, self-advocacy, and peer support. It offers programs designed specifically for college students and young adults with diabetes. The organization offers mentorship, education, and leadership opportunities.
The Takeaway
- There are several types of diabetes, each of which involves high blood glucose levels and is caused by some form of insulin dysfunction.
- The symptoms of diabetes are generally the same regardless of the type because they are all caused by high blood sugar.
- Diabetes is first diagnosed based on an individual’s blood glucose and A1C levels, potentially followed by additional testing to identify the type of diabetes.
- While there isn’t a cure for diabetes, each type can be treated and managed with lifestyle changes, medication, and technology.
Common Questions & Answers
Resources We Trust
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Anna L. Goldman, MD
Medical Reviewer
Anna L. Goldman, MD, is a board-certified endocrinologist. She teaches first year medical students at Harvard Medical School and practices general endocrinology in Boston.
Dr. Goldman attended college at Wesleyan University and then completed her residency at Icahn School of Medicine at Mount Sinai Hospital in New York City, where she was also a chief resident. She moved to Boston to do her fellowship in endocrinology at Brigham and Women's Hospital. She joined the faculty after graduation and served as the associate program director for the fellowship program for a number of years.

Ginger Vieira
Author
Ginger Vieira has lived with type 1 diabetes and celiac disease since 1999, and fibromyalgia since 2014. She is the author of Pregnancy with Type 1 Diabetes, Dealing with Diabetes Burnout, Emotional Eating with Diabetes, and Your Diabetes Science Experiment.
Ginger is a freelance writer and editor with a bachelor's degree in professional writing, and a background in cognitive coaching, video blogging, record-setting competitive powerlifting, personal training, Ashtanga yoga, and motivational speaking.
She lives in Vermont with a handsome husband, two daughters, and a loyal dog named Pedro.