What Are Liver Spots (Age Spots)?

Liver spots are more common in individuals older than 50 but can also appear in younger adults who have experienced significant sun exposure. They tend to develop gradually over time and don’t fade on their own. While liver spots aren’t harmful, it’s critical to distinguish them from more serious skin conditions such as melanoma, a dangerous skin cancer.
Signs and Symptoms of Liver Spots
- Flat, oval-shaped patches
- Light to dark brown in color, which may vary depending on skin tone and sun exposure
- Common on sun-exposed areas such as the face, hands, shoulders, and upper back
- Painless and nonitchy, with no accompanying symptoms such as redness, swelling, or discomfort
- Freckle-size to over a centimeter in diameter
- Clustered together, forming larger pigmented areas over time
Liver spots are usually harmless, but it’s essential to monitor them for any changes in shape, size, or color. If a spot becomes irregular, grows rapidly, or changes in pigmentation, it may be a sign of melanoma, a serious form of skin cancer. Regular skin self-examinations and dermatological checkups can identify any concerning changes early.
Causes and Risk Factors of Liver Spots
- Ultraviolet (UV) Exposure The primary cause of liver spots, sun exposure stimulates melanin production, leading to pigmentation changes over time.
- Aging As the skin matures, its ability to regulate melanin diminishes, leading to pigmentation irregularities.
- Genetic Predisposition Some individuals inherit a higher likelihood of developing liver spots.
- Tanning Beds Artificial UV exposure can contribute to the development of liver spots the same way sunlight does.
- Skin Type People with lighter skin tones are more prone to liver spots because they have less melanin to protect against UV damage naturally.
- Frequent Sunburns A history of repeated sunburns increases your likelihood of developing liver spots later in life.

How Are Liver Spots Diagnosed?
It’s important to see a professional to have the spots on your skin examined in order to distinguish benign patches like liver spots from potentially dangerous skin conditions.
- Visual examination, assessing the size, shape, and color of the spots
- Dermoscopy, a magnified skin examination to differentiate liver spots from malignant conditions
- Skin biopsy, a small skin sample taken if there’s any concern about potential skin cancer
Treatment and Medication Options for Liver Spots
Medication Options
Topical bleaching agents are most commonly used to reduce the appearance of liver spots. Your dermatologist may recommend:
- A prescription bleaching agent, such as a hydroquinone cream, to lighten liver spots
- A retinoid cream, paired with a bleaching agent, to promote skin cell turnover and further reduce pigmentation
- A steroid cream, usually only paired with a bleaching agent, to reduce potential skin irritation caused by the bleaching agent and support the lightening of the skin
- Over-the-counter fade creams that contain hydroquinone, glycolic acid, or kojic acid
Dermatological Procedures
Liver spots can also be treated with the following dermatological procedures:
- Chemical Peels These procedures exfoliate the top layer of skin, allowing for new, less pigmented skin to emerge.
- Laser Therapy Concentrated light is used to target excess melanin. This technique reduces the appearance of liver spots over multiple sessions.
- Cryotherapy This procedure involves freezing the pigmented skin cells, which then peel off and reveal new skin underneath.
- Microdermabrasion and Dermabrasion These skin resurfacing techniques remove the outer layer of skin to improve pigmentation.
Prevention of Liver Spots
- Use a broad-spectrum sunscreen (SPF 30+) daily, even on cloudy days.
- Wear protective clothing and wide-brimmed hats to shield the skin from the sun.
- Stop any use of tanning beds, which expose the skin to artificial UV rays.
- Integrate antioxidants into your skin-care regimen with vitamin C and vitamin E serums to support overall skin health and reduce oxidative stress.
Lifestyle Changes for Managing Liver Spots
You can further support your overall skin health with these steps:
- Incorporate gentle exfoliants like glycolic acid to promote skin cell turnover.
- Consume foods rich in antioxidants, such as berries, green tea, and leafy greens, to protect skin cell health.
- Stay hydrated to maintain skin elasticity and promote cell regeneration.
How Long Do Liver Spots Last?
Liver spots are permanent and won’t go away without treatment. They typically don’t get larger after first forming, but liver spots may slowly continue to darken with age and additional sun exposure.
The Takeaway
- Liver spots or age spots (solar lentigines), a common skin condition caused by exposure to the sun, are harmless.
- You may be able to prevent the formation of liver spots with proper sun protection and skin care.
- While liver spots don’t require treatment, it’s possible to lighten their appearance with a variety of topical treatments and dermatological procedures.
- Liver spots should be evaluated by a doctor to ensure they aren’t a sign of a more dangerous skin condition. If any spot changes in size, shape, or color, seek dermatological evaluation.
Resources We Trust
- Cleveland Clinic: Best Ingredients and Products for Your Anti-Aging Skin Care Routine
- American Academy of Dermatology Association: What Can Get Rid of Age Spots?
- UCDavis Health: Want to Get Rid of Age Spots? Tips to Prevent and Reduce Dark Spots
- Mayo Clinic: Age Spots (Liver Spots)
- Skin Cancer Foundation: 7 Surprising Signs of Sun Damage
- Age Spots (Liver Spots). Mayo Clinic. February 11, 2022.
- Age Spots and Dark Marks. American Academy of Dermatology Association.
- Signs of Premature Aging. Cleveland Clinic. May 23, 2022.
- Photoaging: What You Need to Know About the Other Kind of Aging. Skin Cancer Foundation. June 7, 2021.
- Can Basal and Squamous Cell Skin Cancers Be Found Early? American Cancer Society. October 31, 2023.
- Age Spots (Liver Spots). Mayo Clinic. February 11, 2022.
- Sun Protection: Your Daily Sun Protection Guide. Skin Cancer Foundation. June 2021.
- Pullar JM et al. The Roles of Vitamin C in Skin Health. Nutrients. August 12, 2017.
- Houshmand EB. Effect of Glycolic Acid, Phytic Acid, Soothing Complex Containing Emulsion on Hyperpigmentation and Skin Luminosity: A Clinical Evaluation. Journal of Cosmetic Dermatology. March 2021.
- Michalak M. Plant-Derived Antioxidants: Significance in Skin Health and the Ageing Process. International Journal of Molecular Sciences. January 6, 2022.
- Palma L et al. Dietary Water Affects Human Skin Hydration and Biomechanics. Clinical, Cosmetic and Investigational Dermatology. August 3, 2015.
- What Can Get Rid of Age Spots? American Academy of Dermatology Association. September 28, 2021.

Jacquelyn Dosal, MD
Medical Reviewer
Jacquelyn Dosal, MD, is a board-certified dermatologist at Skin Associates of South Florida in Coral Gables. She practices general, medical, cosmetic, and surgical dermatology.
Dr. Dosal provides compassionate care to all her patients, listening to their concerns and creating a treatment plan with each patient's priorities and real life in mind.
She is a member of the voluntary faculty at the University of Miami.

Ginger Vieira
Author
Ginger Vieira has lived with type 1 diabetes and celiac disease since 1999, and fibromyalgia since 2014. She is the author of Pregnancy with Type 1 Diabetes, Dealing with Diabetes Burnout, Emotional Eating with Diabetes, and Your Diabetes Science Experiment.
Ginger is a freelance writer and editor with a bachelor's degree in professional writing, and a background in cognitive coaching, video blogging, record-setting competitive powerlifting, personal training, Ashtanga yoga, and motivational speaking.
She lives in Vermont with a handsome husband, two daughters, and a loyal dog named Pedro.