What Is Sleep Deprivation?

We all miss out on sleep now and then, but if you’re consistently losing out on shut-eye, it could lead to a health problem called sleep deprivation.

Signs and Symptoms of Sleep Deprivation
- Daytime sleepiness
- Fatigue
- Weakness or decreased physical strength
- Decreased ability to fight infections or getting sick more often
- Headaches
- Slowed reactions
- Difficulty focusing
- Memory problems
- Irritability
- Carbohydrate and sugar cravings
- Slurred speech
- Hand tremors
- Nystagmus (uncontrolled eye movements)
- Brief periods of falling asleep throughout the day that only last a few seconds (microsleeps)
- Ptosis (drooping eyelids)
- Hallucinations
- Poor judgment
- Impulsive behavior
- Lower pain tolerance
- Symptoms of depression and anxiety
Causes and Risk Factors of Sleep Deprivation
- Shift work, especially night shifts
- Jet lag
- Traveling and sleeping in unfamiliar places, such as hotel rooms
- Variable sleep schedule
- Alcohol use or overuse
- Drinking caffeine late in the day
- Poor sleep hygiene (sleep habits)
- High stress
- Insomnia, a condition causing problems falling asleep and staying asleep
- Sleep apnea, a condition causing frequent incidences of shallow or stopped breathing while asleep
- Restless leg syndrome (RLS), a condition causing an overwhelming urge to move the legs, usually to make unpleasant sensations like tingling or itching go away
- Circadian rhythm disorders, conditions involving disruptions to the body’s internal clock (circadian rhythm), which in turn can throw off your sleep schedule
- Parasomnias, or disruptive sleep disorders like sleepwalking
- Alzheimer’s disease
- Parkinson’s disease
- Mental health disorders, such as depression
- Brain injury
- Pain (acute or chronic)
- Temporary illness or infection, such as the flu
- Age over 65
- Change in schedule
- A new baby
How Is Sleep Deprivation Diagnosed?
- Polysomnography This test, also known as a sleep study, detects pauses in breathing, a common sign of sleep apnea.
- Actigraphy This noninvasive test tracks sleep patterns using a wearable device that detects movements while sleeping.
- Multiple Sleep Latency Test (MSLT) This test measures how quickly a person falls asleep during the day.
- Maintenance of Wakefulness Test (MWT) This test estimates a person’s ability to resist falling asleep in dull situations.
- Electroencephalogram (EEG) This test records brain waves and reveals unusual brain activity that could disturb sleep.
Treatment and Medication Options for Sleep Deprivation
Medication Options
- diphenhydramine (Benadryl)
- doxylamine succinate
- zaleplon (Sonata)
- zolpidem tartrate (Ambien)
- zolpidem tartrate extended-release (Ambien CR)
- eszopiclone (Lunesta)
- clonazepam (Klonopin)
- lorazepam (Ativan)
- temazepam (Restoril)
- amitriptyline (Elavil)
- nortriptyline (Pamelor)
- trazodone (Desyrel)
- mirtazapine (Remeron)
- quetiapine (Seroquel)
- doxepin (Silenor), which is also FDA-approved for insomnia
Breathing Support
- Weight loss
- Positioning with different types of pillows
- Mouthpieces that adjust the jaw
- Airway-widening surgery
Complementary and Integrative Therapies
Always discuss complementary sleep therapies with a healthcare professional before trying them to make sure they’re safe for you.
Sleep Deprivation Prevention
Lifestyle Changes for Sleep Deprivation
Set and Keep a Sleep Schedule
Set Up a Welcoming Sleep Space
Avoid Caffeine and Alcohol Before Bed
Build In Some Wind-Down Time
Exercise Daily
Avoid Over-Napping
Sleep Deprivation Prognosis
Complications of Sleep Deprivation
- Accidents (The U.S. sees about 6,000 fatal car crashes per year due to drowsy driving.)
- Brain damage
- Obesity
- Heart disease
- High blood pressure
- Vascular disease
- Heart attack and stroke
- Anxiety and depression
- Diabetes
- Psychosis
Research and Statistics: Who Develops Sleep Deprivation?
Disparities and Inequities in Sleep Deprivation
Related Conditions of Sleep Deprivation
- Chronic fatigue syndrome, a long-term condition involving constant extreme tiredness
- Narcolepsy, a condition involving difficulty sleeping at night and bouts of intense sleepiness during the day
- Substance abuse
- Depression
- Anxiety
The Takeaway
- Among adults, consistently getting less than seven hours of sleep may lead to daytime drowsiness, headaches, and difficulty concentrating, and increases your risk of serious health conditions like heart disease.
- Addressing the underlying cause of sleep deprivation is key to effective treatment, which may include improved sleep hygiene or medical intervention.
- While some over-the-counter supplements like melatonin may help in the short-term, it’s important to discuss any complementary therapies with your doctor before trying them to make sure they’re the most helpful option for you.
- If you think you may be sleep deprived, let your doctor know. They can help you develop a personalized treatment plan to improve your sleep quality.
Common Questions & Answers
Resources We Trust
- Cleveland Clinic: Here’s What Happens When You Don’t Get Enough Sleep
- Mayo Clinic: Lack of Sleep: Can It Make You Sick?
- Harvard Health: Why Sleep Matters: Consequences of Sleep Deficiency
- Johns Hopkins Medicine: The Effects of Sleep Deprivation
- Cedars-Sinai: Sleep Deprivation
- Sleep Deprivation. Cleveland Clinic. August 11, 2022.
- Schriber AD et al. Sleep Deprivation. Cedars-Sinai.
- Hanson JA et al. Sleep Deprivation. StatPearls. June 12, 2023.
- Jet Lag Disorder. Mayo Clinic. November 19, 2022.
- Clever SL. Sleep Aids. The Johns Hopkins University.
- Sleeping Pills. Cleveland Clinic. June 22, 2024.
- PDQ Supportive and Palliative Care Editorial Board. Sleep Disorders. July 2024.
- Bounds CG et al. Benzodiazepines. StatPearls. January 30, 2024.
- DeKosky ST et al. The Long and the Short of Benzodiazepines and Sleep Medications: Short-Term Benefits, Long-Term Harms? Neurotherapeutics. January 2020.
- Korkatti-Puoskari N et al. Therapeutic Dilemma’s: Antipsychotics Use for Neuropsychiatric Symptoms of Dementia, Delirium and Insomnia and Risk of Falling in Older Adults, a Clinical Review. European Geriatric Medicine. July 2023.
- Sleep Apnea Treatment. National Heart, Lung, and Blood Institute. January 09, 2025.
- CPAP. National Heart, Lung, and Blood Institute. March 24, 2022.
- Melatonin. Mayo Clinic. August 10, 2023.
- Sleep Deprivation and Deficiency - Healthy Sleep Habits. National Heart, Lung, and Blood Institute. March 24, 2022.
- Zheng D et al. Alcohol Consumption and Sleep Quality: A Community-Based Study. Public Health Nutrition. October 2021.
- Gardiner C et al. The Effect of Caffeine on Subsequent Sleep: A Systematic Review and Meta-Analysis. Sleep Medicine Reviews. June 2023.
- McCallum K. Caffeine & Sleep: How Long Does Caffeine Keep You Awake? Houston Methodist. July 7, 2023.
- Full Proof: Explaining How Alcohol Can Interfere With Sleep. Cleveland Clinic. January 30, 2025.
- The Effects of Sleep Deprivation. The Johns Hopkins University.
- Adjaye-Gbewonyo D et al. Sleep Difficulties in Adults: United States, 2020. Centers for Disease Control and Prevention. June 22, 2022.
- Summer JV. Sleep Deprivation: Symptoms, Treatment, & Effects. Sleep Foundation. March 7, 2025.

Chester Wu, MD
Medical Reviewer
Chester Wu, MD, is double board-certified in psychiatry and sleep medicine. He cares for patients through his private practice in Houston, where he provides evaluations, medication management, and therapy for psychiatric and sleep medicine conditions.
After training at the Baylor College of Medicine and Stanford University School of Medicine, Dr. Wu established the first sleep medicine program within a psychiatric system in the United States while at the Menninger Clinic in Houston.

Abby McCoy, RN
Author
Abby McCoy is an experienced registered nurse who has worked with adults and pediatric patients encompassing trauma, orthopedics, home care, transplant, and case management. She is a married mother of four and loves the circus — that is her home! She has family all over the world, and loves to travel as much as possible.
McCoy has written for publications like Remedy Health Media, Sleepopolis, and Expectful. She is passionate about health education and loves using her experience and knowledge in her writing.