Understanding Rheumatoid Arthritis Flare-Ups: Symptoms, Triggers, and Management Techniques

Understanding Rheumatoid Arthritis Flare-Ups: Symptoms, Triggers, and Management Techniques
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More than just a condition that causes achy joints, rheumatoid arthritis (RA) is a chronic inflammatory disorder that can affect a person’s life in profound ways.

People with RA seesaw between periods where their joints feel good, and times when symptoms intensify or flare, sometimes making it difficult to get out of bed. If you have RA, identifying what triggers these flare-ups, recognizing their symptoms, and learning effective management strategies is key to minimizing flares’ impact on your life.

What Is a Rheumatoid Arthritis Flare-Up?

A flare-up is a period of increased disease activity during which your RA symptoms worsen beyond the usual day-to-day levels. Unlike the baseline discomfort or joint pain of RA, flares often hit hard, causing joint pain and stiffness that can leave you feeling immobilized, despite treatment.

Flare-ups come in two primary flavors: predictable and unpredictable.

Predictable flares are caused by known triggers, such as poor sleep, stress, and infections like the flu. These flares usually resolve over time on their own, especially if you address the trigger, such as by improving your sleep or managing your stress better.

Unpredictable flares, as their name implies, pop up without a known trigger. These flares might not get better over time, requiring instead changes to your medication to get your disease back under control.

Whether predictable or unpredictable, flare-up intensity can range from mild (a slight increase in joint stiffness and pain) to severe (debilitating pain that makes even simple tasks feel impossible). The flare may last just a few hours or it may last a few weeks to months (if there are no changes in your medications).

Recognizing Symptoms of a Flare-Up

Flares don’t always arrive with a warning, so tuning into your body is essential. Keep track of your usual symptoms, including what they are, how severe they are, and how long they last. You can do this by simply writing it down in a notebook or journal, or by using one of various apps and digital tools available. By keeping a symptom journal, you can spot when things change and know when you might be heading into a flare-up.

When you experience an RA flare, it may feel like your medications or treatments are not working as effectively as before. The same symptoms you had when first diagnosed may reappear or increase in severity, including:

  • Fatigue and decreased energy
  • Increased joint pain, tenderness, and swelling
  • Joint stiffness, especially in the morning upon first waking up
  • Reduced range of joint motion
  • Changes in mood, including irritability, aggression, and depression

  • Mental fogginess

  • Low-grade fever

  • Loss of appetite or weight

Some research suggests the joints you use the most are usually the ones most affected by a flare, including those of the hands and wrists (especially your dominant hand); weight-bearing joints such as the knees, ankles, and feet; and the joints in your neck.

Identifying Triggers of Rheumatoid Arthritis Flare-Ups

Pinpointing what sets off a flare can be tricky, as triggers can differ from person to person and range from environmental and lifestyle factors, to biological causes, to behavioral and dietary issues. Common culprits include:

  • Cold, damp weather, which tends to exacerbate joint pain and stiffness
  • Stress, which can lead to a chain reaction in the body, worsening inflammation
  • Poor sleep
  • Infections or illness, such as the common cold and flu, which can provoke the immune system
  • Hormonal changes, such as during menstruation or menopause
  • Smoking

  • Overexertion from physical activity
  • Exposure to environmental pollutants, toxins, or chemical agents, such as asbestos, sawdust, pesticides, and cleaning detergents

There is no substantial evidence that specific foods can cause an RA flare, but certain foods can increase your risk of inflammation, such as red meat, refined carbohydrates, and foods high in sugar or trans fat.

Diagnosing a Flare

Diagnosing a flare can be tricky, because there’s no strict definition for an RA flare in the scientific literature, and patients and physicians may define or perceive what an RA flare is differently. Because of this, diagnosis is often based on your experiences and how you communicate them to your doctor.

Keeping a symptom diary is critically important when trying to diagnose a flare. Symptoms like pain, joint stiffness, and fatigue are common themes in RA flares, but the duration, severity, and frequency of these symptoms vary widely between patients.

Your symptom diary should be as detailed as possible and may include information such as:

  • How severe your RA pain is according to a scale of your choosing (such as 0 to 10)
  • How your symptoms are affecting your activities, such as causing you to skip work, school, or social activities
  • How your symptoms change as you move and what factors increase or decrease your symptoms
  • How your symptoms respond to over-the-counter medications for pain or inflammation, such acetaminophen, ibuprofen, and naproxen

  • How your symptoms are affecting you emotionally
  • What you were doing when your symptoms first starting getting worse
It can also be helpful to keep track of any changes in your life around the time the potential flare started, including those involving your relationships, work or school, medications, diet, physical activity, and sleep.

Be specific when describing your symptoms to your physician. Instead of making broad statements like “I feel tired,” use specific language like “I’ve had no energy to get out of bed for two days.” It may also be helpful to describe your symptoms using comparative language — some people liken their joint pain to a toothache or being repeatedly hit with a hammer. Clear, detailed communication helps your physician better understand your ailments and how to help you.

Your physician may order tests to find evidence of a flare, such as blood tests and imaging tests like X-rays and ultrasound to look for signs of active or increased inflammation. Keep in mind, however, that a physician’s assessment may not align with your subjective experiences.

Effective Management Techniques for Flare-Ups

When a flare hits, taking action early can make a big difference.

Immediate Steps

Some steps you can take immediately and on your own to soothe or manage your symptoms include:

  • Resting up and engaging in relaxation techniques, such as deep breathing and guided imagery, to release both physical tension and emotional stress
  • Using heat or cold therapy — heat to relax stiff muscles or cold to reduce swelling
  • Taking a hot shower or gently stretching to relieve morning stiffness
  • Using assistive devices such as splints and braces, walking canes, and button hooks, as needed

  • Distracting yourself from the pain by engaging in an activity you enjoy (that doesn’t heavily rely on your problematic joints) and keeping your mind busy while doing other activities

Also remember to lean on your support system. While your loved ones may not be able to take away your pain or other symptoms, they can help you with day-to-day activities, especially those that could make your symptoms worse.

Pharmaceutical Interventions

Various medications can also help to reduce symptoms. Always consult with your healthcare provider before starting new medications or changing your dosages of current medications.

Over-the-counter or prescription-strength pain relievers and nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, naproxen, acetaminophen, and aspirin, can help provide quick relief for mild pain and inflammation during an RA flare.

If you’re experiencing severe symptoms during your flare-up, your provider may recommend low-dose corticosteroids like prednisone, given by injection if your symptoms are localized or orally if your symptoms cover more than one area of your body. These drugs can quickly reduce inflammation, but high-dose or long-term use of steroids can pose serious health risks.

Disease-modifying antirheumatic drugs, or DMARDs, are another class of medication used to treat RA. If you have RA, your treatment plan will likely include one or more DMARDs. These drugs, however, don’t treat specific symptoms of RA — they instead help slow the progression of the disease by modifying the immune system activity behind inflammation. Switching to a different DMARD while experiencing a flare will likely not provide relief in the short term, because DMARDs in general take time to work. Switching may even worsen the flare initially, but it could also shorten the flare by weeks or months and help prevent future flare-ups.

Biologics are a more advanced type of DMARDs that target specific biological processes or molecules that cause RA-related inflammation. If you’re experiencing an RA flare with significant symptoms or one that’s not adequately controlled by other medications, your provider may start you on a biologic along with or instead of other drug therapies.

Holistic and Lifestyle Approaches

Other holistic and lifestyle approaches to treat your RA flare include:

  • Improving your sleep hygiene for better sleep, such as by establishing set sleep and wake times, creating a comfortable sleep environment that’s dark and cool, and avoiding heavy meals before bed

  • Eating anti-inflammatory foods, such as those rich in omega-3 fatty and antioxidants, and avoiding those that promote inflammation

  • Engaging in gentle physical activity, such as hand exercises, swimming, and low-impact tai chi or yoga
  • Adjusting your overall response to pain through mindfulness practices, deep breathing exercises, and counseling or psychotherapy

Long-Term Strategies to Minimize Flare-Ups

While flares can’t always be avoided, adopting proactive habits can reduce their frequency and impact. These include:

  • Regular checkups with your care team to monitor disease activity and adjust treatment as needed
  • Prioritizing rest and stress reduction or management
  • Following a healthy, anti-inflammatory diet, such as the Mediterranean diet

  • Creating a personalized action plan with your care team so you know what steps to take when a flare strikes

  • Maintaining exercise and physical activity, but listen to your body and rest when needed
  • Building a strong support system of family, friends, or RA support groups

The Takeaway

  • Managing rheumatoid arthritis flare-ups involves recognizing symptoms, identifying triggers, and employing effective management strategies.
  • Immediate actions like resting and using heat or cold therapy can provide some relief during flares.
  • Persistent or severe symptoms may require a reevaluation of medication by a healthcare professional.
  • Using a comprehensive approach that includes lifestyle adjustments and medication can help minimize the impact of future flare-ups.
Sian-Yik-Lim-bio

Sian Yik Lim, MD

Medical Reviewer
Sian Yik Lim, MD, is a board-certified rheumatologist at Hawaii Pacific Health. He is a clinical certified densitometrist, certified by the International Society of Clinical Densitometry. He completed his rheumatology fellowship at Massachusetts General Hospital and was also a research fellow at Harvard Medical School. His research interests include osteoporosis, gout, and septic arthritis. Dr. Lim has published in JAMA, Current Opinions in Rheumatology, Osteoporosis International, Bone, Rheumatology, and Seminars in Arthritis and Rheumatism.

Lim has authored several book chapters, including one titled “What is Osteoporosis” in the book Facing Osteoporosis: A Guide for Patients and their Families. He was also an editor for Pharmacological Interventions for Osteoporosis, a textbook involving collaboration from a team of bone experts from Malaysia, Australia, and the United States.

Joseph Bennington-Castro

Author

Joseph Bennington-Castro is a science writer based in Hawaii. He has written well over a thousand articles for the general public on a wide range topics, including health, astronomy, archaeology, renewable energy, biomaterials, conservation, history, animal behavior, artificial intelligence, and many others.

In addition to writing for Everyday Health, Bennington-Castro has also written for publications such as Scientific American, National Geographic online, USA Today, Materials Research Society, Wired UK, Men's Journal, Live Science, Space.com, NBC News Mach, NOAA Fisheries, io9.com, and Discover.

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. What Is an RA Flare? RheumatoidArthritis.net. February 2024.
  2. Understanding Rheumatoid Arthritis Flares. Arthritis Foundation.
  3. Rheumatoid Arthritis Flare-Ups: What to Know and How to Cope. MYA Care. October 11, 2023.
  4. Bykerk VP et al. Flares in Rheumatoid Arthritis: Frequency and Management. A Report from the BRASS Registry. The Journal of Rheumatology. February 2014.
  5. Jara S. Rheumatoid Arthritis Pain and Flare-Ups: What to Know and Do. Creaky Joints. August 28, 2020.
  6. Marill MC. Coping With an Arthritis Flare. Arthritis Foundation. April 21, 2021.
  7. Donvito T. Arthritis Flare-Ups: What Causes Them and Exactly What to Do When You Have One. Creaky Joints. December 24, 2018.
  8. Yaku A et al. Relationship between handedness and joint involvement in rheumatoid arthritis. Scientific Reports. December 15, 2016.
  9. Doumen M et al. Definitions of rheumatoid arthritis flare and how they relate to patients’ perspectives: A scoping review of qualitative and quantitative evidence. Seminars in Arthritis and Rheumatism. May 25, 2024.
  10. Hart N. RA Flare or RA. RheumatoidArthritis.net. December 14, 2022.
  11. Jara S. Rheumatoid Arthritis Pain: 7 Things You Should Tell Your Rheumatologist. Creaky Joints. August 28, 2020.
  12. Stone JH. How Long Does a Flare Last? Arthritis Foundation.
  13. Managing Flares. National Rheumatoid Arthritis Society.
  14. What’s the Best Diet for Rheumatoid Arthritis? Cleveland Clinic. November 20, 2022.
  15. Tips for Managing an Arthritis Flare . Arthritis Foundation.