Does Hand Sanitizer Expire?

Hand sanitizer is a vital tool for killing germs, especially in situations where soap and water aren’t available. In a pinch, a squirt or two can be the difference between staying healthy and getting sick. It makes sense to stock up.
This raises the question, does hand sanitizer really expire, or does it keep working even after the date on the bottle? Keep reading to find out how this product kills germs, why the expiration date matters, and how to properly store hand sanitizer to maximize shelf life.
How Does Hand Sanitizer Kill Germs?
Hand sanitizers are typically alcohol-based rubs containing ethanol or isopropyl alcohol at concentrations between 60 and 95 percent. Alcohol disrupts the cell membrane of bacteria and viruses, causing them to break down.
Non-alcohol-based hand sanitizers contain antimicrobial agents like triclosan or benzalkonium chloride. While they can kill germs, they tend to be less potent than alcohol-based formulas, particularly against viruses like the flu or coronavirus.
What Does 'Expiration' Mean for Hand Sanitizer?
Expiration dates on products like medications and cosmetics refer to the point at which the manufacturer can no longer guarantee the product’s full safety or effectiveness.
With hand sanitizers, the active ingredient (such as alcohol) slowly evaporates over time. Once levels drop below 60 percent, the hand sanitizer becomes significantly less effective.
Shelf Life of Hand Sanitizer
A few factors can shorten how long a bottle of hand sanitizer retains its potency:
- Opening the bottle: Alcohol is volatile, meaning it evaporates. Once the cap on the sanitizer has been opened, the alcohol levels will slowly decrease, reducing the product’s effectiveness.
- High temperatures: Hand sanitizer should not be stored at temps above 105 degrees; you wouldn’t want to keep it in a car during the summer months.
To keep hand sanitizer at full strength, follow these tips:
- Store it in a cool, dry place away from direct sunlight or heat.
- Keep bottles tightly sealed to prevent alcohol from evaporating.
- Rather than buying in bulk, purchase only what you and your family might use within a year or two.
How to Know If a Bottle Is Still Good
To determine whether your hand sanitizer is still effective, check the expiration date on the label. This will give you an idea of how much longer the product will work at its full strength.
Is It Safe to Use Expired Hand Sanitizer?
Can I Throw Away Expired Hand Sanitizer?
The Takeaway
- Hand sanitizer can lose its effectiveness over time, due to the evaporation of the alcohol in it and exposure to heat or sunlight.
- To keep your hand sanitizer working at its best, store it in a cool, dry place, and make sure the cap is tightly sealed to prevent the alcohol from evaporating.
- While expired hand sanitizer is unlikely to cause harm, it may not provide full protection — so, for optimal germ-killing power, it’s important to replace it once it’s past its expiration date.
Resources We Trust
- Mayo Clinic: Infectious Diseases A-Z: Does Hand Sanitizer Kill Flu and Cold Germs?
- Cleveland Clinic: Your Comprehensive Guide to Hand Sanitizer
- Centers for Disease Control and Prevention: About Handwashing
- U.S. Food and Drug Administration: Safely Using Hand Sanitizer
- UCLA Health: Handwashing vs. Hand Sanitizer: What’s the Difference?
- Safely Using Hand Sanitizer. U.S. Food and Drug Administration. April 12, 2023.
- Q and A for Consumers: Hand Sanitizers and COVID-19. U.S. Food and Drug Administration. May 17, 2022.
- Expired Hand Sanitizer Is OK to Use. Lawrence Berkeley National Laboratory. May 17, 2023.
- Does Hand Sanitizer Expire? Gojo Blog. May 8, 2023.
- How to Dispose of and Recycle Alcohol-Based Hand Sanitizer. Environmental Protection Agency. December 10, 2024.

Jane Yoon Scott, MD
Medical Reviewer
Jane Yoon Scott, MD, is an infectious disease physician and an assistant professor of medicine at Emory University in Atlanta. Dr. Scott enjoys connecting with her patients, empowering them to understand and take ownership of their health, and encouraging them to ask questions so that they can make informed and thoughtful decisions.
She graduated with the highest honors from the Georgia Institute of Technology, then received her MD from the Medical College of Georgia. She completed her internal medicine residency training and chief residency at Temple University Hospital, as well as a fellowship in infectious diseases at Emory University. She is board-certified in both internal medicine and infectious diseases.
When she is not seeing patients, Dr. Scott works with neighboring health departments to promote public health, especially to communities that have been historically underserved. She also teaches medical trainees and lectures medical students at the Emory University School of Medicine.
In her free time, Dr. Scott appreciates a good coffee shop, weekend hikes, playing guitar, strolling through cities, sampling restaurants, and traveling to new places.

Becky Upham
Author
Becky Upham has worked throughout the health and wellness world for over 25 years. She's been a race director, a team recruiter for the Leukemia and Lymphoma Society, a salesperson for a major pharmaceutical company, a blogger for Moogfest, a communications manager for Mission Health, a fitness instructor, and a health coach.
Upham majored in English at the University of North Carolina and has a master's in English writing from Hollins University.
Upham enjoys teaching cycling classes, running, reading fiction, and making playlists.