These Online Pharmacies Can Make Getting Your Prescription So Much Easier

With the widespread use of telemedicine since the COVID-19 pandemic, you no longer have to rely on in-person doctor visits and conventional pharmacy trips to fill your prescriptions. While online pharmacies have existed for many years, the pandemic increased accessibility and expanded options for prescription delivery. “Telehealth, as a supplement to a standard in-person care delivery model, is convenient, cost-effective, and improves access to care,” says Amanuel Kehasse, PharmD, PhD, an assistant professor of medicine at Boston University and the director of clinical programs and drug information at Clearway Health.

Not only can online pharmacies save you time — they also often pass on savings to consumers, since they don’t have the same overhead costs as traditional brick-and-mortar locations. While some accept insurance, others maximize patient savings by offering discounted prices on generic versions of medications. To help you find the best online pharmacies, we spoke with two licensed pharmacists and spent countless hours researching and comparing options. Here are our top picks.

Our Top Picks for Best Online Pharmacies

Best for GLP-1s

Ro

Pros

  • Multiple GLP-1 options available
  • User-friendly online platform with virtual consultations
  • Can use your insurance if eligible
  • Membership includes health coaching and unlimited provider messaging
  • First month’s prescription sent to a local pharmacy

Cons

  • Membership fees are expensive
  • Cost of medication is not included in membership
  • Must be an active member to get refills
  • Price of medication increases as dose increases

Key Specs

  • Accepts insurance: Yes
  • Membership required: Yes, $145 monthly
  • Offers telehealth appointments: Yes
  • Prescription types: Brand names and generics
  • Local pickup availability: For some
  • Shipping options: Free shipping
Research has shown that GLP-1s effectively help those who are overweight or have obesity lose weight by suppressing appetite and slowing digestion.

A study published in 2025 found that GLP-1 users lost up to an average of 17.8 percent of their body weight after 72 weeks, compared with those who received a placebo.

 If you’re interested in GLP-1s, the telehealth platform Ro offers a program called the Ro Body membership, which includes access to GLP-1s (if the provider deems it appropriate) and other weight loss tools.

The Ro Body membership costs $45 for the first month and $145 per month after that — though the membership price does not include the cost of the medication itself. The fee goes toward virtual visits with a healthcare provider, assistance with insurance coverage, and health coaching to support your weight loss journey. The cost of GLP-1s varies depending on the specific medication, your insurance coverage, and the dosage.

According to the company, single-dose vials of Zepbound cost between $349 and $499 per month, depending on the dose. Compounded semaglutide costs around $254, while the cash price of Ozempic is $900 or more. The only way to get exact price estimates is to complete the short questionnaire on the company’s website and go through the onboarding process to get a personalized treatment plan with estimated costs, meaning you’ll be out the $45 consultation fee in any case. Also, be aware that compounded GLP-1s are not approved by the U.S. Food and Drug Administration (FDA) and may have potential risks.

Onboarding involves verifying insurance coverage and messaging a provider about your goals and health status. If you’re a candidate for GLP-1 therapy, the provider will then prescribe your medication. However, in many cases, people need a prior authorization from their insurance company before they can fill the prescription. While Ro has a dedicated team to help you through this process, there’s no guarantee that your insurance will cover the cost of GLP-1 therapy. If this happens, you will have the option to pay cash or cancel your membership with Ro. As noted above, the initial $45 consultation fee is nonrefundable.

While having more convenient access to GLP-1 medication is useful, Henry Cohen, PharmD, FCCM, a pharmacist and the dean at Touro College of Pharmacy, emphasizes the importance of seeing your doctor in person before beginning weight loss therapy. “A patient should have a thorough examination for cardiovascular diseases, diabetes, thyroid disease, and behavioral disorders,” he says. Blood tests, psychiatric screening, and physical exams are all vital components of determining whether weight loss medication is appropriate for you.

spilled colorful prescription pills

Best for Price Matching

Blink Health

Pros

  • Free shipping
  • No membership fees
  • Option for local pharmacy pickup or home delivery
  • Licensed pharmacists available to answer questions
  • Will refund the difference if you find a lower price at another online pharmacy

Cons

  • Does not accept insurance
  • No option for express shipping
  • Not up front about prices of brand-name medications

Key Specs

  • Accepts insurance: No
  • Membership required: No
  • Offers telehealth appointments: No
  • Prescription types: Generics
  • Local pickup availability: Yes, through 35,000+ participating pharmacies
  • Shipping options: Free home delivery

Blink Health is an online pharmacy that delivers low-cost generic medications to fill valid prescriptions from your existing doctor. If you order your prescription from Blink Health and find a lower cost at a competing U.S. online pharmacy for the same drug and dosage, you can submit a claim for a refund of the difference, which is why it’s our pick for the best online pharmacy for price matching.

Blink Health offers free home delivery or local pickup through more than 35,000 participating pharmacies. If you opt for retail pickup, the pharmacy you choose will need a copy of your prescription. For home delivery, your doctor can send a copy of your prescription directly to Blink Health via phone, fax, or e-Rx. Once your prescription is in place, Blink Health’s website enables you to search generic medications and compare prices. Once you complete your purchase through the site, the pharmacy team at Blink Health handles the rest. Most home delivery items are delivered within three to seven business days.

Through our research, we found that customers generally appreciate Blink Health for its cost savings. However, you may find yourself waiting a week or longer to receive medications when shipped. But depending on the savings, it may be worth planning ahead to utilize this service.

It’s also worth noting that although Blink Health doesn’t take insurance and dispenses only generic medications, its separate digital pharmacy, BlinkRx, accepts insurance and prescribes certain brand-name specialty medications — including those that require special handling, administration, or monitoring.

Best for Antibiotics

PlushCare

Pros

  • Same-day virtual appointments available
  • Options for many commonly prescribed medications
  • Ability to see provider credentials and reviews before scheduling
  • Treatment for acute conditions like urinary tract infections and sinus infections
  • Accepts insurance

Cons

  • Must have a membership
  • Same-day availability varies based on your location
  • Cannot prescribe controlled substances
  • No guarantee that the provider will prescribe antibiotics

Key Specs

  • Accepts insurance: Yes
  • Membership required: Yes, $19.99 monthly or $99 annually
  • Offers telehealth appointments: Yes
  • Prescription types: Brand names and generics
  • Local pickup availability: Yes
  • Shipping options: Local pickup only

PlushCare may be a good option if you’re in need of same-day antibiotics or other acute treatments, such as Tamiflu for influenza or Paxlovid for COVID-19. The process is simple: You book a virtual appointment with one of the licensed healthcare providers in your state, discuss your symptoms and medical history, and, if appropriate, the provider will send a prescription to your local pharmacy.

To use this service, you must sign up for a membership, which costs $19.99 per month or $99 annually (but you can add your family to your membership for free). Telehealth appointments with a board-certified provider cost $129 without insurance or for your copay fee if you have in-network insurance. You can choose your provider based on available appointment times, specialties, and previous patient reviews.

If the provider decides to prescribe a medication, they will send your prescription to the local pharmacy of your choice. Shipping and delivery are not available, unless the pharmacy you pick has delivery services. The provider may recommend other medications or treatments, which you can discuss during your appointment.

Our research found that most customers are impressed by PlushCare’s convenience and fast service, though some report having to wait days for an appointment, difficulty with providers, and occasional technical issues with the website. That said, it may be a good option if you need antibiotics or another acute treatment quickly.

Best for Birth Control

Hers

Pros

  • Access to 12+ oral contraceptives
  • Telehealth appointments offered
  • Products shipped in discreet packaging
  • Option to add on nonprescription products to your order
  • Ability to enroll in auto-shipping

Cons

  • Does not accept insurance
  • May be more expensive than others
  • Limited prescription options for sexually transmitted infections
  • Messaging may be less personal than in-person consults

Key Specs

  • Accepts insurance: No
  • Membership required: No
  • Offers telehealth appointments: Yes
  • Prescription types: Generics
  • Local pickup availability: Yes
  • Shipping options: Free shipping

If you’re looking for a discreet way to manage your sexual health, we recommend Hers. The platform offers more than a dozen oral birth control options, including generic versions of Lutera, Junel 1.5/30, Microgestin 1.5/30, Larin Fe 1.5/30, and Yaz. The website breaks down each option with feature tags such as “treating acne,” “period pain,” and “skipping periods.”

In addition to birth control options, Hers also offers lubricants, condoms, supplements for libido, and even personal pleasure products. Everything is discreetly shipped directly to your door. And while some products don’t require a prescription, others may need a virtual consultation with a healthcare provider on the platform. Those interested in birth control pills can sign up for a plan starting at $12 per pack, with the option to cancel or change the subscription at any time.

To find the exact cost of your medication, you’ll need to complete the short questionnaire on the website to see which birth control options may be a good fit. You can browse each to learn more about the benefits and potential side effects. However, it’s important to note that Hers also offers treatments for several other conditions (weight loss, mental health, hair regrowth), and each category has different subscription options, so it’s a bit difficult to navigate the site and estimate your costs if you’re interested in more than one of its programs.

Customers are happy with platform’s services overall, especially its ease of use and convenience. However, based on our research, you may experience shipping delays and difficulty contacting support when an issue arises. Despite this, it may be worth considering if you’re looking for birth control at a low monthly price.

Best for ED Treatment

Hims

Pros

  • Offers prescriptions for stamina and erectile dysfunction
  • Chewable and oral tablets available
  • Private consultations with licensed physicians
  • Takes only a few minutes to sign up
  • Affordable pricing for generic options

Cons

  • Does not accept insurance
  • Shipping can take up to seven business days
  • Difficult to talk to a provider outside of messaging

Key Specs

  • Accepts insurance: No
  • Membership required: No
  • Offers telehealth appointments: Yes
  • Prescription types: Brand names and generics
  • Local pickup availability: Yes
  • Shipping options: Free shipping; $5 flat fee for nonprescription products
Up to 50 million men in the U.S. experience erectile dysfunction (ED), a condition that can make it difficult to achieve or maintain an erection. Anything from aging and stress to chronic health conditions like diabetes can interfere with the way your body responds to sexual stimulation.

 For some, taking prescription medication can help improve erectile function. However, many men are more comfortable seeking treatment online because it’s fast and confidential. Hims offers a convenient way to improve your sex life without visiting a primary care physician.

ED medications from Hims include generic chewable and oral versions of popular drugs like Viagra and Cialis. Its Sex Rx + Climax Control pills can also help prolong sexual activity and prevent premature ejaculation. These products are prescribed by licensed physicians and delivered to your home for free. You can also add other non-Rx goods to your order, like condoms and lubricants, and Hims offers treatments for hair loss, skin care, and mental health as well.

Like Hers, its women’s wellness counterpart, Hims uses a subscription model for sexual health treatment. Depending on the medication, you could pay as little as $1.30 per mint-flavored chewable or more than $33 per pill for name-brand Cialis. Tadalafil, the active ingredient in Cialis, is also available as a generic option through Hims for $49 per month. You can take a quick assessment on the website to see if you’re a candidate for any of the products, and if so, schedule a consultation with a licensed physician.

The platform does not accept insurance, so if you have health coverage that covers ED treatment, Hims may be more expensive than it would be to get it elsewhere.

closeup shot of hand using laptop with pill containers in the foreground

Best for Brand-Name Drugs

Amazon Pharmacy

Pros

  • Sells brand-name and generic drugs
  • Amazon Prime members get discounts and free two-day shipping
  • Accepts insurance
  • Ability to enroll in automatic refills
  • 24/7 pharmacist support

Cons

  • You need an Amazon Prime membership to get the lowest price
  • RxPass annual membership includes only 53 eligible medications
  • Limited inventory of certain medicines, including GLP-1s
  • Doesn’t offer compounded medications

Key Specs

  • Accepts insurance: Yes
  • Membership required: No, but Prime members get the most savings
  • Offers telehealth appointments: Yes
  • Prescription types: Brand names and generics
  • Local pickup availability: No
  • Shipping options: Free two-day shipping and $2.99 same-day delivery for Prime members; free four-to-five-day shipping or $5.99 two-day shipping for non-Prime members

If you take name-brand medications and have an Amazon Prime membership, we recommend Amazon Pharmacy. With a wide selection of brand-name and generic drugs, discounts for Prime members, and in-network status with most commercial insurance plans, the platform offers the convenience we know and love from its retail counterpart. Plus, same-day delivery is available in some areas for $2.99.

Other perks include automatic refills, 24/7 on-call support from U.S.-licensed pharmacists, and the option to have your medications sorted into PillPacks with the date and time for easy dispensing. You must have three or more eligible daily medications filled through Amazon to take advantage of the PillPacks, but the service itself is free.

Amazon also offers an RxPass membership, which gives Prime members unlimited access to medications and refills of certain prescription drugs. At the time of writing, there were 53 eligible medications. RxPass costs $5 per month, in addition to the $139 annual cost of a Prime membership.

Those without a Prime membership still get free standard shipping but do not get discounted prices on medications. Non-Prime members can expect to pay the listed retail price, if paying out of pocket. Both prices are listed on the product page for each medication, along with an estimated insurance price based on what customers have paid for the medication when using insurance at the Amazon Pharmacy.

blue and white pills suspended in air

Most Affordable

Honeybee Health

Pros

  • Ability to select the medication’s form, strength, and quantity
  • Multiple generic medication manufacturer options
  • Platform recommends supplements based on your prescriptions
  • Offers over-the-counter pharmacy products
  • Can upgrade shipping if needed

Cons

  • Free shipping on orders over $40; $5 shipping free on orders under $40
  • No price matching
  • Doesn’t accept insurance

Key Specs

  • Accepts insurance: No
  • Membership required: No
  • Offers telehealth appointments: No
  • Prescription types: Generics
  • Local pickup availability: No
  • Shipping options: Free shipping on orders over $40; $5 for standard delivery on orders under $40, $15 for FedEx Priority, or $35 for FedEx Express

Honeybee Health is an online pharmacy with up-front pricing on generic medications from different manufacturers. We like that it lists the available manufacturers alongside specific dietary tags like “contains no gluten” or “contains no dyes,” so you can choose the option that best suits your needs. The site offers a wide range of generic medications for conditions like anxiety, depression, hypothyroidism, migraine, high blood pressure, and more.

Honeybee also offers over-the-counter pharmacy items, such as its branded Honeybee Health supplements and generic acetaminophen (Tylenol). The website also has a feature that suggests supplements based on the prescription medications in your cart. For example, if you have atorvastatin (Lipitor) in your cart, the website recommends a coenzyme Q10 (CoQ10) supplement. A meta-analysis published in 2018 found that CoQ10 supplementation can help treat muscle pain, weakness, tiredness, and cramps caused by statin drugs.

Honeybee Health doesn’t accept insurance, and you have to pay for shipping on orders less than $40. The standard USPS rate is $5, but you can upgrade to FedEx Priority for $15 (two to three days) or Express (one to two days) for $35.

Our research found that customer feedback is fairly positive. Many reviewers mention the service being more affordable than their local pharmacy. On the downside, there are some complaints about delayed deliveries, high prices on certain drugs, and issues with refunds or missed shipments.

spilled colorful prescription pills

Best for Filling Multiple Prescriptions

DiRx

Pros

  • Offers annual savings plans to help you save on select medications
  • One flat fee covers the cost of multiple medications
  • Free shipping
  • Ability to enroll in automatic refills
  • Can order up to a six-month supply

Cons

  • Doesn’t accept insurance
  • No returns of any kind
  • Shipping may take longer than some competitors

Key Specs

  • Accepts insurance: No
  • Membership required: No
  • Offers telehealth appointments: No
  • Prescription types: Generics
  • Local pickup availability: No
  • Shipping options: Free two-to-seven-day delivery, $15 UPS 2nd Day, and $30 UPS Next Day

DiRx is an online pharmacy that sells discounted generic prescription medications. Its Annual Savings Plan, which is similar to Amazon RxPass, covers the cost of unlimited prescriptions and refills on select medicines. This membership starts at $180 annually and covers up to 500 eligible medications. It’s an affordable way to order and refill multiple prescriptions if you take more than one type of medication.

There are two DiRx savings plans. The $180 per-year Annual Savings Plan has 500 eligible medications, while the $360 per-year Annual Savings Plus Plan has 1,000 eligible medications. If your medications are eligible for either plan, you’ll pay one flat fee for the year. People with several eligible medications benefit more from it, so it’s important to price out your medications and compare your options before committing to a membership. Without a savings plans, you’ll pay the DiRx everyday low price. Standard shipping is free, with the option to upgrade to second-day or overnight shipping at an additional cost.

While this service has many pros, it is worth noting that customer reviews are mixed. Some users have reported long wait times and problems transferring prescriptions from other pharmacies. If you take multiple eligible prescriptions, though, the potential price savings may make it a worthwhile option for you.

Best for People With Insurance

Express Scripts

Pros

  • Offers 90-day supplies on select medications
  • In-network with many major insurance plans
  • May cost less than monthly refills
  • Convenient app for managing prescriptions
  • Ability to enroll in automatic refills

Cons

  • Cannot use this service without a participating health plan
  • Cannot handle controlled substances
  • Some medications don’t qualify for home delivery
  • Any delay in your order could result in running out of medication

Key Specs

  • Accepts insurance: Yes
  • Membership required: No, but you need an in-network health plan
  • Offers telehealth appointments: No
  • Prescription types: Brand names and generics
  • Local pickup availability: Yes
  • Shipping options: Free standard shipping

Express Scripts is an online home-delivery pharmacy that works with your insurance company to deliver 90-day supplies of generic and name-brand medications with current prescription orders from your doctor. The company is one of the largest pharmacy benefit management organizations in the United States.

One of the most significant advantages of Express Scripts is that they accept most major insurance plans, including Aetna, UnitedHealthcare, and Cigna. However, you must check with your pharmacist and health plan to ensure that they are in-network with Express Scripts, as the service isn’t available to customers with out-of-network plans. Additionally, some medications don’t qualify for home delivery in 90-day supplies, so you won’t be able to use the service in those cases.

If your medication qualifies, you can easily sign up for the service online and manage your prescriptions. Three-month supplies are often less expensive than a month’s supply at a time, but you’ll want to compare pricing to make sure it’s worth it.

The downsides to Express Scripts are that the service is limited to select medications, and sometimes the savings aren’t very significant. Our research also found quite a few complaints about customer service quality and delivery delays, so don’t use this service without doing your research first. Still, if your health plan partners with Express Scripts for 90-day drug supplies, it’s worth considering because you could save a lot of money under the right circumstances.

Best for Anxiety Medication

RedBox Rx

Pros

  • Offers several generic anxiety medications for $25 per month
  • No membership or subscription fees
  • Can use health savings and flexible spending accounts
  • Free shipping
  • Pay-as-you-go therapy available

Cons

  • Must be 18 years or older
  • Does not accept insurance
  • Must order as a three-month supply for maximum savings

Key Specs

  • Accepts insurance: No
  • Membership required: No
  • Offers telehealth appointments: Yes
  • Prescription types: Brand names and generics
  • Local pickup availability: Yes
  • Shipping options: Free shipping; expedited shipping is available for an additional fee

Unlike the mental health platforms that require a monthly subscription or membership fee to access medication, RedBox Rx offers flexible medication management and therapy. You can purchase anxiety medication after a $35 virtual consultation with a licensed medical professional, as long as the provider agrees that medication is appropriate.

Medication options include buspirone, citalopram, duloxetine, hydroxyzine (for anxiety-related insomnia), paroxetine, venlafaxine ER, and others. A 90-day supply of each of these costs $25 per month (with the exception of hydroxyzine, which costs $16.66 per month for 90 tablets). Medications are also available for adult attention deficit hyperactivity disorder, depression, and performance anxiety.

To use the service, you’ll need to fill out the request form with your preferred medication, strength, quantity, and refill preferences. The tool will display the cost of one fill, not including the $35 consult fee. After reviewing the cost and confirming your selection, you’ll be directed to create an account and request an appointment with a doctor.

RedBox Rx isn’t a replacement for a professional psychiatrist or mental health provider. You shouldn’t use services like this if you have any severe mental health concerns. However, those who have been diagnosed with a mild form of anxiety may find this platform more affordable and convenient than brick-and-mortar options.

Best for Preventive Drugs

HealthWarehouse

Pros

  • 3,000+ prescription drugs available
  • Offers competitive cash pricing
  • 10-minute grace period for canceling orders
  • Ships free in 3 to 11 business days
  • Upgraded shipping options available for a fee

Cons

  • Takes up to five days to process new prescriptions
  • Some specialty medications are not available
  • No local pickup option

Key Specs

  • Accepts insurance: No
  • Membership required: No
  • Offers telehealth appointments: No
  • Prescription types: Brand names and generics
  • Local pickup availability: No
  • Shipping options: Free for prescriptions and over-the-counter orders over $15; $5 standard shipping for over-the-counter orders under $15; either may also be shipped for $10 expedited, $15 two-day, or $25 overnight

If you’re looking for an online pharmacy with great prices and an extensive selection of prescription and over-the-counter meds, HealthWarehouse is a solid choice. It offers more than 3,000 name-brand and generic prescription medications, including options for high cholesterol, high blood pressure, and diabetes (even insulin). The company does not accept insurance, to keep costs as low as possible for those who pay out of pocket.

Compared with the cash price at traditional pharmacies, HealthWarehouse’s prices are often significantly lower. For example, a 30-day supply of generic 10-milligram lisinopril costs $9 at HealthWarehouse, compared with an average of $16.63 at local pharmacies, per the GoodRx pricing tool. Savings vary depending on the medication and your local pharmacy’s pricing, but you save even more when purchasing larger quantities.

To order through HealthWarehouse, you need a valid prescription from your doctor. Add the medications you wish to purchase to your cart (make sure the dosage and quantity match your prescription), and proceed to checkout. HealthWarehouse will contact your prescriber to verify your prescription, and once it’s approved, your order is shipped to your door. Prescription orders ship for free, as do over-the-counter orders over $15. For over-the-counter orders under $15, the shipping fee is $5 for standard delivery within the United States. You can also upgrade to expedited shipping for an additional fee. Refrigerated items and insulin are shipped via overnight air, which is included in the pricing.

Through our research, we found that it’s easy to see how much your medication will cost before making any commitments, and many reviewers praise the platform’s customer service and fast delivery. However, there were a few complaints about delayed shipments from the postal service and technical issues with the website. Still, HealthWarehouse has some of the most positive reviews we’ve seen.

Comparison Table

Best For
Insurance
Membership
Telehealth appointments offered
Prescription types
Local pickup available
Shipping options
GLP-1s
Yes
Yes, $145 monthly
Yes
Brand names and generics
For some
Free shipping
Price matching
No
No
No
Generics
Yes, through 35,000+ participating pharmacies
Free home delivery
Antibiotics
Yes
Yes, $19.99 monthly or $99 annually
Yes
Brand names and generics
Yes
Local pickup only
Birth control
No
No
Yes
Generics
Yes
Free shipping
ED treatment
No
No
Yes
Brand names and generics
Yes
Free shipping; $5 flat fee for nonprescription products
Name-brand drugs
Yes
No, but Prime members get the most savings
Yes
Brand names and generics
No
Free 2-day shipping and $2.99 same-day delivery for Prime members; free 4-to-5-day shipping or $5.99 2-day shipping for non-Prime members
Most affordable
No
No
No
Generics
No
Free shipping on orders over $40; $5 for standard delivery on orders under $40, $15 for FedEx Priority, or $35 for FedEx Express
Filling multiple prescriptions
No
No
No
Generics
No
Free 2-to-7-day delivery, $15 UPS 2nd Day, $30 UPS Next Day
People with insurance
Yes
No, but you need an in-network health plan
No
Brand names and generic
Yes
Free standard shipping
Anxiety medication
No
No
Yes
Brand names and generics
Yes
Free shipping; expedited shipping is available for an additional fee
Preventive drugs
No
No
No
Brand names and generics
No
Prescriptions ship free; over-the-counter orders over $15 ship free; over-the counter orders under $15 ship for $5 standard shipping; orders may also be shipped for $10 expedited, $15 2-day, or $25 overnight

What to Look for When Choosing an Online Pharmacy

There are several key factors to consider when choosing an online pharmacy:

  • Licensing: Make sure the pharmacy is appropriately licensed and accredited. According to Dr. Cohen, an online pharmacy should be state-licensed and preferably accredited by the National Association of Boards of Pharmacy, while compounding pharmacies should be FDA-registered. “The FDA does not directly certify online pharmacies and relies on state licensing boards to verify their legitimacy and safety,” Cohen explains. You can confirm the pharmacy’s license by checking the board of pharmacy licenses databases by state.
  • Reputation: The best way to gauge a company’s reputation is to read customer reviews from sources outside of its website, including online forums where people go to talk about their experiences. Potential red flags may include poor customer service, delayed shipping that is not the carrier’s fault, and hidden fees.
  • Prescription requirements: Federal law requires pharmacies to verify your prescription before dispensing the medication. You should never use a pharmacy that doesn’t abide by this, as it’s against the law and could mean they’re distributing unsafe medications.
  • Available medications: Some pharmacies stock only select medications or may only sell generic versions. Make sure that your chosen pharmacy carries all of the medications you need (or as many as possible) before signing up. If it’s a membership platform, you will likely save more money with one that has a wider selection.
  • Customer service: Check the customer service hours and verify that there are multiple ways to contact customer service, including a valid U.S. phone number, should a problem arise. Online pharmacies with 24/7 customer service may be a better option for those who prefer immediate assistance.
  • Privacy: A website’s privacy policy is typically located in the lower part of its navigation menu. Look for a statement clearly explaining how your personal and medical information will be protected. Also, check to see if third-party companies are allowed to access your information.
  • Delivery options: Some online pharmacies offer free or expedited shipping for an additional fee. Check the estimated delivery time so you can plan your deliveries accordingly.

What Are the Risks of Using an Online Pharmacy?

Online pharmacies can be safe if you choose a reputable company where the “prescription orders are coming from legitimate, qualified, and accredited providers with access to past medical and treatment history of the patient,” says Dr. Kehasse. That’s not to say using one is without risk.

Cohen cautions that using an online pharmacy could result in:

  • Delivery issues
  • Lack of transparency regarding pricing and costs
  • Inability to provide medications based on state laws after paying for a consultation
  • Inability or difficulty reaching the provider or pharmacy by phone
  • Subscription cancellation problems
  • Incorrect diagnosis
  • Incorrect medication for diagnosis
  • Fake doctor allegations
The FDA warns that online pharmacies may sell counterfeit, expired, or otherwise unsafe medications. These products could cause irreversible harm. It advises consumers to only purchase from websites that require a prescription, have a U.S.-based address and contact information, have a licensed pharmacist available for questions, and are licensed with a state board of pharmacy.

Similarly, the U.S. Department of Justice released a statement in 2024 regarding a lawsuit against a group of individuals involved in a scheme to manufacture and distribute counterfeit prescription drugs through online pharmacies. The drugs were either entirely fake or contained harmful substances that could lead to life-threatening consequences.

Using websites that provide prescription medication after filling out a simple questionnaire can also be dangerous, according to a review published in 2021 in American Health & Drug Benefits.

 For example, some people might have undiagnosed health conditions that require a thorough evaluation before starting a new medication, such as Viagra (sildenafil citrate) for erectile dysfunction. Those taking medicines called “nitrates” for chest pain could experience a life-threatening drop in blood pressure if they take Viagra, which a generic questionnaire could miss.

What Drugs Can Doctors Prescribe Online?

It varies based on your provider’s credentials and state laws. In general, online doctors can prescribe medications that are not controlled substances. General categories of drugs that online doctors may prescribe include:

  • Antibiotics
  • Antidepressants
  • Blood pressure and heart medications
  • Cholesterol-lowering medications
  • Contraceptives
  • Erectile dysfunction drugs
  • Insomnia medications
  • Medications for chronic conditions (such as asthma and diabetes)
  • Migraine/headache medications
Controlled substances are medications known to lead to abuse and dependence, such as opioids or stimulants.

 Examples include oxycodone (OxyContin), amphetamine and dextroamphetamine (Adderall), and alprazolam (Xanax).
Recently, the U.S. Drug Enforcement Administration (DEA) announced new telemedicine regulations that enable some providers to prescribe these types of medications to new patients who have not been seen in person. However, specific criteria must be met, such as registering with the DEA and complying with the monitoring process.

Under previous DEA regulations, telemedicine providers could only prescribe controlled substances if they had conducted an in-person examination or already established a prior relationship with the patient, though regulations varied based on the state.

Is It Safe to Use an Online Pharmacy for Mental Health Medications Instead of Seeing a Psychiatrist in Person?

While you may wish to fill your medication through an online pharmacy, it’s generally not recommended that you receive a diagnosis or treatment plan solely through virtual means. Diagnosing a mental health condition often takes several steps, which may include multiple mental health evaluations and psychological tests or therapy sessions. Some research indicates that virtual appointments may not be as effective as in-person sessions.

A study published in 2023 found that certain mental health patients who opted for telehealth appointments had significantly higher no-show rates than those who saw their provider in person.

Additionally, according to a study published in 2022 on the effects of no-show rates on patient outcomes, missed appointments increase the likelihood of psychiatric emergency room visits and hospitalizations.

 Virtual care may not be adequate for those who require close monitoring, such as those with severe symptoms.

Kehasse says that while virtual appointments improve access to care, they are not a good fit for those with complex conditions. Filling medications through an online pharmacy may also increase risks, as it lacks crucial education and support features for patients regarding their medication.

“Some medications used for mental health disorders require special medication administration techniques that are best demonstrated to confirm the patient’s ability to self-administer with a teach-back method, which is difficult to accomplish through an online pharmacy,” Kehasse adds. It may be more practical to see a psychiatrist for a proper diagnosis and initial management, then transition into telehealth for convenience once you are stable on medications.

FAQs

Can I get a prescription online without seeing a doctor?
It depends on the type of prescription you need, your state’s regulations, and the platform you use. Some online services allow you to fill out a detailed health questionnaire that’s reviewed by a licensed healthcare provider. If your case meets the criteria, they can issue a prescription without requiring an in-person visit. However, those with a known health condition or new symptom should see a doctor in person or through a telehealth appointment to ensure safety.
They can be. Your provider should be licensed and operating through a verified platform. Make sure the provider complies with state regulations and that the prescriptions come from a valid source. Platforms promising overly cheap prescriptions should be avoided.
Amazon Pharmacy does not deliver schedule II controlled substances, according to the frequently asked questions on its website. Examples of schedule II controlled substances include “combination products with less than 15 milligrams of hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine, methadone, hydromorphone (Dilaudid), meperidine (Demerol), oxycodone (OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin,” per the DEA.
EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
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  2. Moiz A et al. Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes: A Systematic Review of Randomized Controlled Trials. Annals of Internal Medicine. January 7, 2025.
  3. Definition and Facts for Erectile Dysfunction. National Institute of Diabetes and Digestive and Kidney Diseases. October 2024.
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Lindsay Modglin

Author

Lindsay Modglin is a former nurse and health writer who specializes in covering chronic illness, women's health, oncology, and wellness products that help empower readers to take control of their health and well-being. Her byline has been featured in many digital publications, including Healthline, Verywell Health, Parents, Forbes, Yahoo, AOL, Insider, and more. Her print work has been published in oncology magazines like Cancer Today and Cure.

Prior to becoming a writer, Lindsay started working in healthcare in 2012 as an optician while she was pursuing her nursing license before working as a registered nurse in a clinical healthcare setting. This experience gave her firsthand knowledge of the challenges and complexities that patients face when managing chronic illnesses and navigating the healthcare system.

Today, when Lindsay is not writing, she enjoys camping and traveling across the United States with her husband and three children. She also volunteers as a creative writer for a non-profit organization that supports children with life-threatening illnesses and as a soccer coach for her children's teams.

Kristina D. Carter, PharmD

Medical Reviewer

Kristina D. Carter, PharmD, is a clinical pharmacist and freelance health writer who currently works in a managed care setting, performing quality audits on utilization management case reviews for the pharmacy team. She has over 20 years of experience and has worked in several pharmacy practice settings, including at a community pharmacy as well as in ambulatory care, senior care, and pharmacy operations.

She received her doctor of pharmacy degree from Xavier University of Louisiana College of Pharmacy and her master's of business administration and health administration from Georgia State University Robinson College of Business. She is an American Council on Exercise–certified health coach, group fitness instructor, senior fitness specialist, and weight management specialist. She is also a registered pharmacist, licensed in Georgia, Indiana, and Tennessee.

Dr. Carter enjoys exploring new restaurants with family and friends, walking along city trails, and watching action movies and college sports.

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Daniel Oakley is a journalist, editor, and fact-checker. He has written, edited, taught, and produced media for Dow Jones, S&P Global, IHS Markit, Third Coast Studios Magazine, and 826 National.

Oakley's path has always been a health-and-wellness-focused one. A competitive triathlete and racing fundraiser for the Leukemia and Lymphoma Society, he also spends summer weekends as an ISA-certified surf instructor and Red Cross professional water rescuer with Laru Beya Collective in Rockaway Beach, which helps kids master and delight in their own backyard — the ocean. It has taught Oakley that “optimizing body and mind” flourishes precisely at the wellspring of community.

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Before transitioning into her full-time writing career, Ashley worked in the departments of pediatric cardiology and general medicine at Duke University Medical Center, and later at the North Carolina Medical Board. During undergrad, she majored in communications at Purdue University and then earned her master’s degree with a concentration in healthcare management from Indiana Wesleyan University.

Ashley lives with her husband and two young daughters in North Carolina. In her free time, she enjoys reading, walking, taking barre classes, and catching up on her favorite podcasts.