Hate Going In for a Colonoscopy? These 6 Easy At-Home Colon Cancer Screening Tests Might Save You a Trip
Blood Tests
Other colon cancer screening tests currently under development are at-home blood sample tests. Their low level of accuracy means they are currently not recommended for use in place of FOBT, FIT, or mt-sDNA screening tools.
The three types of doctor-recommended tests are:
- FOBTs look for small amounts of blood in your stool, which may indicate a problem in your digestive tract.
- Lab-tested FITs, such as LabCorp On Demand ColoFIT Home Collection Test and Simple Colon Health Test, use a stool sample collected at home and mailed to a lab for testing.
- Home-tested FITs, such as Diagnox Colonox FIT, Second Generations FIT, and Instant-View iFOB test, use a stool sample both collected and tested at home.
- Stool DNA FITs, such as the Cologuard Kit, use a stool sample collected at home and mailed to a lab. In addition to an FIT, the sample is tested for abnormal DNA that could indicate the presence of colon cancer.
If any of these at-home options sound like something you’re interested in considering, we’re here to help you learn more so that you can, in consultation with your medical provider, figure out which one might be best for your needs. Here is what to know about the expert-recommended at-home options for each type of at-home colon cancer screening test.
When to Consult Your Doctor
It is always recommended that you consult with your medical provider to see if you are a good candidate for an at-home colon cancer screening test. If you are at higher risk due to factors like age, family history, or underlying conditions, colonoscopies are recommended.
A positive at-home FIT, Cologuard, or colon cancer blood test should always be followed up by a visit to a gastroenterologist. None of these tests is a replacement for a colonoscopy: they are a simple, noninvasive way to see if a colonoscopy is necessary.
Blood in the stool can be caused by several diseases besides colon cancer, including diverticulitis, hemorrhoids, inflammatory bowel disease, polyps, and ulcers. So while a positive FIT result does not mean you have cancer, it does mean you need to schedule a colonoscopy.
Lab-Tested FITs
Here are the two lab-tested FITs that are available:

LabCorp On Demand ColoFIT Home Collection Test
Pros
- HSA/FSA payment accepted
- Available to anyone age 18 and over
- Results available online
- Purchase and testing process overseen by healthcare professionals
- Results posted 3–4 days after sample received
Cons
- Slightly higher cost
- Must be done annually
- Not specific to colon cancer
- Only sold on LabCorp site
Key Specs
- Type of sample: Stool
- Type of test: FIT
- Testing method: Mail-in lab analysis
- Follow-up care: Not offered
The LabCorp On Demand ColoFIT test is a great option for anyone looking to screen at home without performing the actual test themselves. With this one, all you have to do is collect your stool sample and mail it to the lab, where a professional administers the FIT and posts the results online.
This adds a few days of suspense before getting your results but removes the potential for user error in administering the test yourself, making it a great option for anyone feeling unsure of the testing process. LabCorp will perform the test and post your results online in your personal account within three to four days of receiving the sample.
Your submission will be reviewed and approved by a healthcare professional. For results that require follow-up care, patients will be contacted by phone and email as well as through their online portal. So while there is no doctor’s visit involved, LabCorp’s service includes some support from actual healthcare providers.

Simple Colon Health Test
Pros
- FSA/HSA accepted
- Free follow-up care for positive results
- Affordably priced
- Available for less at online retailers
Cons
- Not available in New York
- Must be done annually
- Not specific to colon cancer
Key Specs
- Type of sample: Stool
- Type of test: FIT
- Testing method: Mail-in lab analysis
- Follow-up care: Available
Simple Healthkit is a California-based company that offers an at-home FIT with lab analysis. The company was founded by Sheena Menezes, PhD, and aims to make healthcare more accessible by offering integrated care. Its at-home test kits are intended as a starting point to get individuals the care they need.
The company prides itself on having a 100 percent outreach rate for people who receive positive test results. A member of their team is guaranteed to follow up with you to make sure you understand your results. Follow-up treatment is free in cases of a positive result; customers are encouraged to schedule a telehealth appointment through Simple HealthKit to discuss their results and next steps at no charge.
Users described the kit as easy-to-use and straightforward, with results posted online as soon as three days after mailing in the kit. However, the kits are not available in New York State.
In addition to Amazon and Walmart, you can also purchase this test on Simple Healthkit's website.
Home-Tested FITs
With a home-tested kit, you’ll receive one or more test cassettes along with the materials to collect your samples. The test is similar to a COVID test — except instead of swabbing mucus, you’ll be mixing a bit of your stool sample into a liquifying agent and using a dropper to put it onto the test cassette. As with a COVID test, two lines — however faint — mean a positive result, and one line means negative.
Here are the two Home-Tested FIT Tests available:

Diagnox Colonox FIT
Pros
- Results in 10 minutes
- Detects hemoglobin concentrations as low as 45 ng/ml
- FDA-approved for home use
- No need to mail in sample
- Suitable for all ages
Cons
- No support during testing or follow-up care
- Home testing leaves room for user error
- Sample collection paper is flimsy
Key Specs
- Type of sample: Stool
- Type of test: FIT
- Testing method: Conducted at home
- Follow-up care: Not offered
Diagnox offers a variety of at-home test kits for issues like urinary tract infections, kidney disease, and vaginal health. Its tests are designed and priced for repeat use, making this one of the most affordable options on the market. It’s available in multipacks of two or three as well as a single kit.
The test boasts one of the highest sensitivities on the market, detecting concentrations of blood in the stool as low as 45 ng/mL. Some lab-tested kits only detect as low as 100 ng/mL. Results appear in as little as 10 minutes. The kit is approved by the U.S. Food and Drug Administration (FDA).
However, some customers complained of the kit returning no result (no line turning up), while others found the sample collection paper to be too flimsy to properly collect a sample. Also, there’s no follow-up assistance from a healthcare professional.

Pinnacle Biolabs Second Generation FIT (2-pack)
Pros
- FSA/HSA eligible
- Results in 5 minutes
- High user ratings
- Easy sample collection
Cons
- Home testing leaves room for error
- Shipping can be slow
Key Specs
- Type of sample: Stool
- Type of test: FIT
- Testing method: Conducted at home
- Follow-up care: Not offered
The Second Generation FIT is made by Pinnacle BioLabs, an industry leader in at-home FIT. Its accuracy, price, and customer service are all solid, but what truly sets this kit apart is its extra-easy sample collection method.
While most other kits require users to poop on a piece of paper — with many complaints of the paper breaking, and the sample falling into the toilet below, which can lead to a contaminated sample and inaccurate results — this kit pulls the sample off a piece of used toilet paper. This leaves less room for contamination and more room for your dignity. It’s understandable why this has been the top-selling at-home FIT kit for the past four years running, with over 18 million kits sold.

Instant-View iFOB Test (2-pack)
Pros
- Over 99.5 percent accurate
- Results in 1 minute
- Easy sample collection
- Suitable for all ages
Cons
- Home testing leaves room for error
Key Specs
- Type of sample: Stool
- Type of test: FIT
- Testing method: Mail-in lab analysis
- Follow-up care: Not offered
Instant-View’s Immunochemical Fecal Occult Blood Test (iFOB, which is the same as an FIT) is made in California by Alfa Scientific Designs and uses a very small sample, allowing users to conveniently obtain their sample from a piece of used toilet paper.
The test cassette features a patented Driven Flow technology, which squeezes the sample drop up the cassette and through the reaction area at a higher speed than other kits. Not only does this allow you to read the sample results almost immediately — it also maximizes the reaction of the binding complexes. According to Alfa, this improves the accuracy of the result. Sadly, no follow-up care is offered.
Stool DNA FIT Test
The only hybrid DNA FIT test available in the United States right now comes from Cologuard. It runs the same FIT described above, but also tests the sample for abnormal DNA, which is another test completely separate from the FIT. Both tests are done in a lab, and your results are provided online — and as Cologuard requires a prescription, your healthcare provider will follow up with you in case of a positive result.
In addition to boosting the test’s detection rate to 92 percent, the DNA test offers an advantage over the FIT because it's cancer-specific. If it returns a positive FIT result, knowing whether or not the DNA test was also positive would mean a lot while waiting to book your colonoscopy.
The kit can be purchased out-of-pocket, but it costs about $650. However, most people eligible for Cologuard are also eligible for insurance coverage via Medicare or Medicaid; most users pay nothing.

Exact Sciences Cologuard Kit
Pros
- Specifically tests for colon cancer
- Detects 92 percent of colon cancers
- Only needs to be administered every 3 years
- Support from healthcare professionals
- Free with Medicare, Medicaid, and most insurance
Cons
- Requires a prescription
- Not available to anyone under age 45
Key Specs
- Type of sample: Stool
- Type of test: FIT and abnormal DNA
- Testing method: Mail-in lab analysis
- Follow-up care: Available
Like FIT, Cologuard is a stool sample–based test, but in addition to blood, it also tests the stool sample for abnormal DNA caused by cancer, making it even more sensitive than the FIT. Cologuard is only for people ages 45 to 75 with no symptoms and no family history of colon cancer. If you do fall into this group, Cologuard is likely a great option for you.
The kit, manufactured by Exact Sciences, is covered by most forms of insurance, and 96 percent of patients receive it completely free. You will need a doctor’s prescription, but Cologuard can help you with this part, too. The Cologuard website will send you over to Recuro Health, its telehealth partner, to get a doctor’s approval if you appear to be eligible after the online survey.
The test even just got an update — increasing the sensitivity from 92 to 95 percent, meaning better detection for both cancer and precancerous polyps.
A Note About Blood Sample At-Home Colon Cancer Tests
Several at-home cancer screening tests that use blood samples are also available. These multicancer early detection (MCED) tests are created to detect many different cancers, including colon cancer. Blood sample tests look for proteins excreted by cancerous tumors as they grow, known as biomarkers. Many different cancers produce the same biomarkers, making these tests an effective tool for testing for a large number of cancers — including colon cancer — from a single blood draw. If it sounds too good to be true, it might be. MCED tests have a significantly lower sensitivity in detecting colon cancer than the FIT.
Two available blood sample tests:
- OneTest at-home cancer screening costs $200 and looks for seven cancer biomarkers. The sensitivity of the test is 76.9 percent for colon cancer, with an overall sensitivity of 87 percent in testing for the most common cancers, including liver, lung, prostate, pancreas, and colon.
- Galleri, a once hotly anticipated MCED from GRAIL labs, costs $950, has had somewhat disappointing results, and has not received the FDA approval it was hoping to get. Its sensitivity in detecting colon cancer is 66.3 percent, while its overall sensitivity in detecting cancer is 51.5 percent, looking at all types of cancer across all stages.
A blood test specifically for colon cancer was recently released, but it is not available for home use, nor is it proven to be any more effective than at-home stool screening tests such as the FIT.
Comparison Table
What to Look for When Buying At-Home Colon-Cancer Tests
If you’re considering an at-home colon cancer test, there are several important things to take into account. The first is whether an at-home test is a good option for you. Here are some other considerations.
Are You a Good Candidate for an At-Home Colon Cancer Test?
Should You Test at Home or Mail Your Sample to a Lab?
While the FIT cassette available to use at home is the same test as the one used in the lab, mailing your sample in for testing reduces the risk of user error. Of the negative reviews of online tests, many users complain they could not obtain a result (zero lines) from their cassette. The tests work much like a home COVID-19 or home pregnancy test; if you’re not comfortable with those, choosing a service that mails your sample to a lab might be a better option for you.
Are You Eligible for Cologuard?
If you are between ages 45 to 75, insured, and at normal risk for colon cancer, Cologuard is the standout option. It has all the benefits of an at-home FIT, with the added benefit of abnormal DNA testing, and it’s completely covered by most insurance.
What’s the Difference Between an At-Home Colon Cancer Test and a Colonoscopy?
How Accurate Are At-Home Colon Cancer Tests?
What to Do if Your At-Home Colon Cancer Test Is Positive
At What Age Should I Start Using an At-Home Colon Cancer Test?
FAQs
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