7 Melatonin Mistakes Sleep Doctors Want You to Avoid

Note: The U.S. Food and Drug Administration (FDA) does not approve supplements for safety or effectiveness. Talk to a healthcare professional about whether a supplement is the right fit for your individual health, and about any potential drug interactions or safety concerns.
“It’s great that people are focusing on their sleep, and melatonin may help,” says Michael Grandner, PhD, the director of the sleep and health research program at the University of Arizona College of Medicine in Tucson. “But it’s often not used correctly,” he adds.
Melatonin has fewer potential side effects than many prescription sleep aids, and supplements are generally considered safe when taken properly. Your sleep may improve if you avoid these seven common mistakes.
6 Melatonin Mistakes to Avoid
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1. You Don’t Practice Other Good Sleep Hygiene Strategies
Melatonin is one effective option in the sleep toolbox, but it shouldn’t be the only one you try, and it also shouldn’t be the first step you take if you’re not sleeping well, says David Neubauer, MD, an associate professor in the department of psychiatry and behavioral sciences at Johns Hopkins University School of Medicine in Baltimore.
- Go to sleep and wake up at the same time, seven days a week.
- Make your sleeping space dark and quiet.
- Keep the bedroom temperature between 60 and 67 degrees.
- Stop eating two or three hours before bedtime.
- Create a relaxing bedtime routine, with peaceful music, a book, or a warm bath.
2. You Think Melatonin Makes You Sleepy
If you're using it to knock yourself out every night, it won’t. It will help shift your sleep patterns if you’re struggling with things like jet lag or an irregular sleep schedule because of shift work, but it isn’t very effective for insomnia caused by other issues.
3. You Take Melatonin Just Before Bedtime
“It tells your body it’s nighttime,” Grandner says. But it takes a little bit of time for your body to power down, the same way it does when you naturally start to feel sleepy before bed. If you take it right before you turn in, the effect will start too late.
4. You Use Melatonin in the Middle of the Night
If your insomnia means you routinely wake up at 3 a.m, popping a melatonin supplement won’t help you drift back off to sleep. It may be tempting to try it, but this timing is ineffective, because our naturally occurring melatonin hormone levels are at peak levels already, says Naima Covassin, PhD, a sleep researcher at the Mayo Clinic in Rochester, Minnesota.
5. You Take Melatonin Every Night
6. The Dosage Is Too High
“More is not necessarily better,” Covassin says.
As with long-term daily use, high doses may increase the risk of side effects. If you don’t see results with lower doses, talk to a healthcare provider to get to the root of your sleep problems and devise a more effective treatment plan.
7. You Leave It Out in Plain Sight
The Takeaway
- Melatonin supplements are a synthetic version of the drowsy hormone that’s naturally produced in the brain. Melatonin can help improve the body’s natural sleep-wake cycle, but it’s only effective if used properly.
- Common melatonin mistakes include taking them at the wrong time or at the wrong dose. These supplements should also not be relied on as a long-term fix for chronic sleeping problems.
- Melatonin use has become more popular in recent years, and there’s been an increase in the number of children who have accidentally ingested it. Don’t leave melatonin, or any other kind of medicine or supplement, within reach of young children.
- How Much Melatonin Do We Really Take? Sleep Foundation. October 20, 2022.
- Melatonin: What You Need to Know. National Center for Complementary and Integrative Health. May 2024.
- 10 Tips for a Better Night’s Sleep. National Sleep Foundation.
- Melatonin for Sleep: Does It Work? Johns Hopkins Medicine.
- Melatonin Capsules or Tablets. Cleveland Clinic.
- Awake at 3 a.m.? Strategies to Help You to Get Back to Sleep. Harvard Health Publishing.
- Li J et al. Trends in Use of Melatonin in Supplements Among U.S. Adults, 1999-2018. JAMA. February 1, 2022.
- Melatonin. MedlinePlus. July 9, 2024.
- Digital Cognitive Behavioral Therapy for Insomnia: Platforms and Characteristics. American Academy of Sleep Medicine. March 6, 2024.
- Melatonin Dosage: How Much Melatonin to Take. Sleep Foundation. December 20, 2023.
- Keep Your Kids Safe. Centers for Disease Control and Prevention. March 21, 2024.
- Lelak K et al. Pediatric Melatonin Ingestions — United States, 2012–2021. Centers for Disease Control and Prevention. June 3, 2022.

Chester Wu, MD
Medical Reviewer
Chester Wu, MD, is double board-certified in psychiatry and sleep medicine. He cares for patients through his private practice in Houston, where he provides evaluations, medication management, and therapy for psychiatric and sleep medicine conditions.
After training at the Baylor College of Medicine and Stanford University School of Medicine, Dr. Wu established the first sleep medicine program within a psychiatric system in the United States while at the Menninger Clinic in Houston.
